Fentanyl is considered how many times more potent than morphine as an analgesic?

Fentanyl is recognized for its extreme potency as an analgesic, being approximately 100 times more potent than morphine. This potency means that much smaller doses of fentanyl are required to achieve the same pain-relieving effects as larger doses of morphine. This property makes fentanyl an effective option in clinical settings for managing severe pain, particularly in situations where patients have developed a tolerance to other opioids.

In contrast, the other potency levels—50 times, 75 times, and 150 times—do not accurately reflect the established consensus in medical literature about the potency comparison between fentanyl and morphine. The 100 times potency ratio is well-documented in pharmacological references, emphasizing the need for careful dosing and monitoring when fentanyl is used, given its high potential for overdose.